Reference-grade research compound
Semax
Met-Glu-His-Phe-Pro-Gly-Pro
Sequence schematic — no PDB structure deposited
- Scientific name
- Met-Glu-His-Phe-Pro-Gly-Pro
- Sequence
- MEHFPGP
- Length
- 7-mer
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.94 g/mol
- Form
- lyophilized
- Available sizes
- 5 mg, 10 mg
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.6%
Description
Heptapeptide analog of the ACTH(4-7) fragment with a C-terminal Pro-Gly-Pro extension. Used in vitro as a tool compound in BDNF and NGF expression assays in neuronal cell-line model systems. Supplied as a lyophilized acetate salt.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain.
J Neurochem · 2006
PMID 16635254PubMedSemax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus.
Brain Res · 2006
PMID 16996037PubMedSemax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.
Br J Pharmacol · 2025
PMID 40692165PubMed
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