Reference-grade research compound
Semaglutide
Synthetic 31-residue GLP-1 receptor agonist peptide with Aib8 and Arg34 substitutions and a C18 fatty diacid conjugated at Lys26 via a γGlu-(2x AEEA) linker
PDB 4ZGM
- Scientific name
- Synthetic 31-residue GLP-1 receptor agonist peptide with Aib8 and Arg34 substitutions and a C18 fatty diacid conjugated at Lys26 via a γGlu-(2x AEEA) linker
- Sequence
- —
- Length
- 31-mer
- Molecular formula
- C187H291N45O59
- Molecular weight
- 4113.58 g/mol
- Form
- lyophilized
- Available sizes
- 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 2 mg · cartridge (no pen), 5 mg · cartridge (no pen)
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.4%
Description
Synthetic 31-residue GLP-1 analog containing a non-natural aminoisobutyric acid residue and a C18 fatty diacid side chain attached at Lys26. Used in vitro as a reference compound in GLP-1 receptor binding and cAMP accumulation assays in transfected cell-line model systems. Supplied as a lyophilized acetate salt.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
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