Reference-grade research compound
NAD+
β-Nicotinamide adenine dinucleotide, oxidized form, supplied as a buffered fill solution
Schematic — no PDB structure deposited
- Scientific name
- β-Nicotinamide adenine dinucleotide, oxidized form, supplied as a buffered fill solution
- Sequence
- —
- Length
- 0-mer
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.43 g/mol
- Form
- lyophilized
- Available sizes
- 5 mL, 10 mL
- Storage
- Store solution at −20 °C, protected from light; avoid repeated freeze-thaw. Stable for 12 months.
- Batch HPLC purity
- 99.3%
Description
Small-molecule dinucleotide coenzyme consisting of adenine and nicotinamide nucleotides joined through their phosphate groups. Used in vitro as a reference compound in redox-dependent enzyme activity and sirtuin assays in cell-free and cell-line model systems. Supplied as a buffered solution in a choice of fill volumes.
Storage and stability
Store solution at −20 °C, protected from light; avoid repeated freeze-thaw. Stable for 12 months.
Peer-reviewed references
NAD+ and sirtuins in aging and disease.
Trends Cell Biol · 2014
PMID 24786309PubMedNAD⁺ in aging, metabolism, and neurodegeneration.
Science · 2015
PMID 26785480PubMedCD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.
Cell Metab · 2016
PMID 27304511PubMed
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