Reference-grade research compound
MGF
Mechano-growth factor, the C-terminal E-domain peptide of the IGF-1Ec splice variant
Sequence schematic — no PDB structure deposited
- Scientific name
- Mechano-growth factor, the C-terminal E-domain peptide of the IGF-1Ec splice variant
- Sequence
- YQPPSTNKNTKSQRRKGSTFEERK
- Length
- 24-mer
- Molecular formula
- C121H200N42O39
- Molecular weight
- 2867.20 g/mol
- Form
- lyophilized
- Vial size
- 2 mg
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.2%
Description
24-residue peptide corresponding to the unique C-terminal E-domain of the IGF-1Ec (mechano-growth factor) splice variant of insulin-like growth factor 1. Used in vitro as a reference compound in myoblast proliferation and muscle progenitor cell assay model systems. Supplied as a lyophilized acetate salt.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
Growth hormone stimulates mechano growth factor expression and activates myoblast transformation in C2C12 cells.
Kobe J Med Sci · 2008
PMID 18772608PubMedMinireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration.
Endocrinology · 2010
PMID 20130113PubMedMechano-growth factor accelerates the proliferation and osteogenic differentiation of rabbit mesenchymal stem cells through the PI3K/AKT pathway.
BMC Biochem · 2015
PMID 25588515PubMed
Titles and journals pulled from PubMed and cached for 7 days. Links open in a new tab.