Reference-grade research compound
Melatonin
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
Schematic — no PDB structure deposited
- Scientific name
- N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
- Sequence
- —
- Length
- 0-mer
- Molecular formula
- C13H16N2O2
- Molecular weight
- 232.28 g/mol
- Form
- lyophilized
- Vial size
- 10 mg
- Storage
- Store powder at −20 °C, desiccated and protected from light. Stable for 36 months.
- Batch HPLC purity
- 99.1%
Description
A small-molecule indoleamine derivative of serotonin bearing a 5-methoxy group and an N-acetyl side chain. Used in vitro as a reference compound in MT1 and MT2 receptor binding assays and antioxidant radical-scavenging model systems. Supplied as a crystalline powder.
Storage and stability
Store powder at −20 °C, desiccated and protected from light. Stable for 36 months.
Peer-reviewed references
Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent α-synuclein-induced ferroptosis in Parkinson's disease.
J Pineal Res · 2024
PMID 38488331PubMedMelatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views.
J Pineal Res · 2024
PMID 39400423PubMedMT1 Melatonin Receptor Reconstitution in Nanodiscs.
Methods Mol Biol · 2022
PMID 36180690PubMed
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