Reference-grade research compound
HGH 191 AA 97%
Somatropin; recombinant human growth hormone, single-chain 191-residue non-glycosylated polypeptide with two intrachain disulfide bonds
PDB 1HGU
- Scientific name
- Somatropin; recombinant human growth hormone, single-chain 191-residue non-glycosylated polypeptide with two intrachain disulfide bonds
- Sequence
- FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
- Length
- 191-mer
- Molecular formula
- C990H1528N262O300S7
- Molecular weight
- 22124.00 g/mol
- Form
- lyophilized
- Available sizes
- 10 iu, 12 iu, 15 iu, 24 iu
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.5%
Description
Recombinant single-chain 191-residue non-glycosylated polypeptide identical in sequence to pituitary human growth hormone, with two intrachain disulfide bonds. Used in vitro as a reference compound in growth hormone receptor binding and JAK/STAT signaling assays in cultured cell-line model systems. Supplied as a lyophilized powder.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.
Front Endocrinol (Lausanne) · 2018
PMID 29487568PubMedThe growth hormone receptor.
Growth Horm IGF Res · 2016
PMID 26059750PubMedGrowth hormone receptor: structure and signal transduction.
Eur J Endocrinol · 1995
PMID 8548048PubMed
Titles and journals pulled from PubMed and cached for 7 days. Links open in a new tab.