Reference-grade research compound
Dermorphin
Dermorphin; H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2, an amidated heptapeptide containing a D-alanine residue
Schematic — no PDB structure deposited
- Scientific name
- Dermorphin; H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2, an amidated heptapeptide containing a D-alanine residue
- Sequence
- —
- Length
- 7-mer
- Molecular formula
- C40H50N8O10
- Molecular weight
- 802.88 g/mol
- Form
- lyophilized
- Vial size
- 5 mg
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.2%
Description
Amidated heptapeptide originally identified in amphibian skin, notable for a D-alanine residue at position 2. Used in vitro as a reference compound in mu-opioid receptor binding assays and GPCR signaling model systems. Supplied as a lyophilized acetate salt.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
In vitro and in vivo opioid activity of [DPro(6)]dermorphin, a new dermorphin analogue.
Peptides · 2003
PMID 12732340PubMedIn Vitro and In Vivo Pharmacological Profiles of LENART01, a Dermorphin-Ranatensin Hybrid Peptide.
Int J Mol Sci · 2024
PMID 38612817PubMedOpioid peptide-derived analgesics.
AAPS J · 2005
PMID 16353933PubMed
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