Reference-grade research compound
AOD 9604
Modified human growth hormone (177-191) fragment analog with an N-terminal tyrosine substitution and an intramolecular disulfide bridge
Schematic — no PDB structure deposited
- Scientific name
- Modified human growth hormone (177-191) fragment analog with an N-terminal tyrosine substitution and an intramolecular disulfide bridge
- Sequence
- —
- Length
- 16-mer
- Molecular formula
- C78H123N23O23S2
- Molecular weight
- 1815.08 g/mol
- Form
- lyophilized
- Available sizes
- 2 mg, 5 mg, 10 mg
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.8%
Description
Modified 16-residue analog of the C-terminal fragment of human growth hormone, carrying an added N-terminal tyrosine and an intramolecular disulfide bridge. Used in vitro as a reference compound in lipolysis and lipogenic gene-expression assays in adipocyte cell-line model systems. Supplied as a lyophilized acetate salt.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone.
Horm Res · 2000
PMID 11146367PubMedThe effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice.
Endocrinology · 2001
PMID 11713213PubMedDetection and in vitro metabolism of AOD9604.
Drug Test Anal · 2015
PMID 25208511PubMed
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