Reference-grade research compound
Adipotide
Prohibitin-targeting peptide 1 (CKGGRAKDC-GG-D(KLAKLAK)2), a chimeric proapoptotic peptidomimetic
Schematic — no PDB structure deposited
- Scientific name
- Prohibitin-targeting peptide 1 (CKGGRAKDC-GG-D(KLAKLAK)2), a chimeric proapoptotic peptidomimetic
- Sequence
- —
- Length
- 0-mer
- Molecular formula
- C152H252N44O42
- Molecular weight
- 2611.41 g/mol
- Form
- lyophilized
- Available sizes
- 2 mg, 5 mg
- Storage
- Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
- Batch HPLC purity
- 99.3%
Description
Chimeric peptidomimetic linking a cyclic prohibitin-targeting motif to a D-amino-acid proapoptotic (KLAKLAK)2 domain. Used in vitro as a reference compound in receptor-targeted apoptosis assays and vascular cell model systems. Supplied as a lyophilized acetate salt.
Storage and stability
Store lyophilized powder at −20 °C, desiccated and protected from light. Stable for 24 months.
Peer-reviewed references
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.
Sci Transl Med · 2011
PMID 22072637PubMedReversal of obesity by targeted ablation of adipose tissue.
Nat Med · 2004
PMID 15133506PubMedA comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication.
J Control Release · 2013
PMID 23871959PubMed
Titles and journals pulled from PubMed and cached for 7 days. Links open in a new tab.